STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0282Predicted coding region TP0282; Hypothetical protein; identified by Glimmer; putative. (239 aa)    
Predicted Functional Partners:
TP_0304
Predicted coding region TP0304; Hypothetical protein; identified by Glimmer; putative.
  
  
 0.929
cmk
Ribosomal protein S1 (rpsA); Similar to SP:P02349 GB:V00342 GB:V00352 GB:X04864 PID:42837 percent identity: 36.77; identified by sequence similarity; putative.
  
    0.899
TP_0281
Predicted coding region TP0281; Hypothetical protein; identified by Glimmer; putative.
       0.773
TP_0280
Predicted coding region TP0280; Hypothetical protein; identified by Glimmer; putative.
       0.727
rlpA
Rare lipoprotein A, putative; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.
   
 
 0.613
TP_0278
Predicted coding region TP0278; Hypothetical protein; identified by Glimmer; putative.
       0.590
TP_0623
Membrane-bound lytic murein transglycosylase D (dniR); Similar to SP:P23931 GB:X60739 PID:1208972 PID:581068 GB:U00096 percent identity: 32.28; identified by sequence similarity; putative.
    
  0.567
tig
Trigger factor (tig); Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase (By similarity). Belongs to the FKBP-type PPIase family. Tig subfamily.
  
    0.511
tpn50
Outer membrane protein (tpn50); Could function as a porin; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
  
  
 0.500
prc
Carboxyl-terminal protease (ctp); Similar to PID:559865 PID:1657989 percent identity: 37.36; identified by sequence similarity; putative; Belongs to the peptidase S41A family.
  
    0.496
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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