STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TP_0289Predicted coding region TP0289; Hypothetical protein; identified by Glimmer; putative. (534 aa)    
Predicted Functional Partners:
TP_0285
Predicted coding region TP0285; Hypothetical protein; identified by Glimmer; putative.
 
    0.953
TP_0078
Spore coat polysaccharide biosynthesis protein (spsC); Similar to GB:X73124 SP:P39623 PID:413989 GB:AL009126 percent identity: 40.58; identified by sequence similarity; putative; Belongs to the DegT/DnrJ/EryC1 family.
  
 
 0.939
TP_0288
Spore coat polysaccharide biosynthesis protein (spsF); Similar to GB:X73124 SP:P39626 PID:413992 GB:AL009126 percent identity: 31.88; identified by sequence similarity; putative.
    0.932
spsE
Spore coat polysaccharide biosynthesis protein (spsE); Similar to GB:X73124 SP:P39625 PID:413991 GB:AL009126 percent identity: 27.64; identified by sequence similarity; putative.
  
  
 0.926
wecE
Spore coat polysaccharide biosynthesis protein, putative; Similar to PID:1653135 percent identity: 23.08; identified by sequence similarity; putative; Belongs to the DegT/DnrJ/EryC1 family.
 
 
 0.876
TP_0261
Catabolite gene activator, putative; Similar to PID:1653345 percent identity: 30.99; identified by sequence similarity; putative.
 
 
  0.858
TP_0286
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 27.92; identified by sequence similarity; putative.
  
  
 0.828
TP_0287
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 28.03; identified by sequence similarity; putative.
  
  
 0.828
TP_0284
Predicted coding region TP0284; Hypothetical protein; identified by Glimmer; putative.
  
    0.813
glyA
Serine hydroxymethyltransferase (glyA); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
   
  0.796
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.