STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TP_0290Conserved hypothetical protein; Similar to GP:1418999 percent identity: 27.07; identified by sequence similarity; putative. (277 aa)    
Predicted Functional Partners:
ribF
Riboflavin kinase/FMN adenylyltransferase (ribF); Similar to GB:U00096 PID:1786208 percent identity: 31.05; identified by sequence similarity; putative.
   
 0.777
TP_0551
Phosphatase; Similar to GB:L25421 PID:409159 percent identity: 32.50; identified by sequence similarity; putative.
    
 0.751
gph
Phosphoglycolate phosphatase (gph-2); Similar to GB:L42023 SP:P44755 PID:1004013 PID:1222502 PID:1204815 percent identity: 32.55; identified by sequence similarity; putative.
    
  0.725
TP_0291
Predicted coding region TP0291; Hypothetical protein; identified by Glimmer; putative.
 
     0.723
TP_0736
Hydrogenase, gamma chain (hydG); Similar to GB:L77117 PID:1592091 percent identity: 36.32; identified by sequence similarity; putative.
   
 
  0.694
tpn50
Outer membrane protein (tpn50); Could function as a porin; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
       0.651
surE
Survival protein, putative; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
  0.645
thrS
threonyl-tRNA synthetase (thrS); Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
     
  0.645
prs
Phosphoribosyl pyrophosphate synthetase (prs); Similar to GB:AE000783 percent identity: 44.86; identified by sequence similarity; putative; Belongs to the ribose-phosphate pyrophosphokinase family.
  
    0.642
TP_0293
Predicted coding region TP0293; Hypothetical protein; identified by Glimmer; putative.
       0.634
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.