STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0291Predicted coding region TP0291; Hypothetical protein; identified by Glimmer; putative. (293 aa)    
Predicted Functional Partners:
TP_0939
Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative.
  
 
 0.988
accC
Phosphoribosylglycinamide formyltransferase, putative; Similar to GB:X78962 SP:P39771 PID:534939 GB:AL009126 percent identity: 30.04; identified by sequence similarity; putative.
 
   
  0.945
prs
Phosphoribosyl pyrophosphate synthetase (prs); Similar to GB:AE000783 percent identity: 44.86; identified by sequence similarity; putative; Belongs to the ribose-phosphate pyrophosphokinase family.
    
  0.888
TP_0683
Octaprenyl-diphosphate synthase; Similar to GP:2072008 percent identity: 100.00; identified by sequence similarity; putative; Belongs to the FPP/GGPP synthase family.
 
 
 0.828
TP_0295
Carhohydrate kinase (xylB); Similar to GB:AE000783 percent identity: 28.85; identified by sequence similarity; putative.
  
  
 0.822
ldhD
D-specific D-2-hydroxyacid dehydrogenase; Similar to GP:1644433 percent identity: 42.48; identified by sequence similarity; putative.
  
 
 0.819
cmk
Ribosomal protein S1 (rpsA); Similar to SP:P02349 GB:V00342 GB:V00352 GB:X04864 PID:42837 percent identity: 36.77; identified by sequence similarity; putative.
  
 
 0.808
tpn50
Outer membrane protein (tpn50); Could function as a porin; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
       0.773
TP_0293
Predicted coding region TP0293; Hypothetical protein; identified by Glimmer; putative.
       0.752
ispH
Penicillin tolerance protein (lytB); Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
    
 0.745
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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