STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0295Carhohydrate kinase (xylB); Similar to GB:AE000783 percent identity: 28.85; identified by sequence similarity; putative. (414 aa)    
Predicted Functional Partners:
rpe
Ribulose-phosphate 3-epimerase (cfxE); Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate; Belongs to the ribulose-phosphate 3-epimerase family.
    
 0.970
TP_0291
Predicted coding region TP0291; Hypothetical protein; identified by Glimmer; putative.
  
  
 0.822
prs
Phosphoribosyl pyrophosphate synthetase (prs); Similar to GB:AE000783 percent identity: 44.86; identified by sequence similarity; putative; Belongs to the ribose-phosphate pyrophosphokinase family.
     
 0.794
gnd
Phosphogluconate dehydrogenase (gnd); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
    
 0.793
rpiA
Ribose 5-phosphate isomerase (rpiA); Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
    
 0.760
tpn50
Outer membrane protein (tpn50); Could function as a porin; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
 
     0.750
pgl
Glucose-6-phosphate 1-dehydrogenase, putative; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
   
 0.727
TP_0293
Predicted coding region TP0293; Hypothetical protein; identified by Glimmer; putative.
       0.718
TP_0408
Predicted coding region TP0408; Hypothetical protein; identified by Glimmer; putative.
 
     0.691
ldhD
D-specific D-2-hydroxyacid dehydrogenase; Similar to GP:1644433 percent identity: 42.48; identified by sequence similarity; putative.
  
 
 0.666
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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