STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rfuAExported protein (tpn38b); Probably part of the ABC transporter complex RfuABCD involved in riboflavin import. Binds riboflavin. (343 aa)    
Predicted Functional Partners:
rfuB
Ribose/galactose ABC transporter, ATP-binding protein (rbsA-1); Probably part of the ABC transporter complex RfuABCD involved in riboflavin import. Probably responsible for energy coupling to the transport system.
 
 
 0.998
rfuC
Conserved hypothetical integral membrane protein; Probably part of the ABC transporter complex RfuABCD involved in riboflavin import. Probably responsible for the translocation of the substrate across the membrane.
 
 
 0.998
rfuD
Conserved hypothetical integral membrane protein; Probably part of the ABC transporter complex RfuABCD involved in riboflavin import. Probably responsible for the translocation of the substrate across the membrane.
 
 
 0.998
TP_0323
Ribose/galactose ABC transporter, permease protein (rbsC-2); Similar to GB:AE000783 percent identity: 32.47; identified by sequence similarity; putative; Belongs to the binding-protein-dependent transport system permease family.
 
 
 0.878
TP_0321
Ribose/galactose ABC transporter, ATP-binding protein (rbsA-2); Similar to GB:AE000783 percent identity: 39.48; identified by sequence similarity; putative.
 
 
 0.870
TP_0299
Predicted coding region TP0299; Hypothetical protein; identified by Glimmer; putative.
     
 0.858
TP_0322
Ribose/galactose ABC transporter, permease protein (rbsC-1); Similar to GB:AE000783 percent identity: 29.58; identified by sequence similarity; putative; Belongs to the binding-protein-dependent transport system permease family.
 
 
 0.853
TP_0297
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 22.81; identified by sequence similarity; putative.
     
 0.643
TP_0295
Carhohydrate kinase (xylB); Similar to GB:AE000783 percent identity: 28.85; identified by sequence similarity; putative.
 
     0.597
TP_0408
Predicted coding region TP0408; Hypothetical protein; identified by Glimmer; putative.
  
  
  0.579
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.