TP_0299 protein (Treponema pallidum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

TP_0299

Predicted coding region TP0299; Hypothetical protein; identified by Glimmer; putative. (74 aa)

Predicted Functional Partners:

rfuB

0.884

rfuD

0.884

rfuC

0.863

rfuA

0.845

TP_0297

0.727

coaE

0.490

Your Current Organism:

Treponema pallidum

NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
TP_0297	TP_0299	TP_0297	TP_0299	Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 22.81; identified by sequence similarity; putative.	Predicted coding region TP0299; Hypothetical protein; identified by Glimmer; putative.	0.727
TP_0297	coaE	TP_0297	TP_0296	Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 22.81; identified by sequence similarity; putative.	Conserved hypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.	0.857
TP_0297	rfuA	TP_0297	TP_0298	Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 22.81; identified by sequence similarity; putative.	Exported protein (tpn38b); Probably part of the ABC transporter complex RfuABCD involved in riboflavin import. Binds riboflavin.	0.626
TP_0297	rfuB	TP_0297	TP_0300	Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 22.81; identified by sequence similarity; putative.	Ribose/galactose ABC transporter, ATP-binding protein (rbsA-1); Probably part of the ABC transporter complex RfuABCD involved in riboflavin import. Probably responsible for energy coupling to the transport system.	0.703
TP_0297	rfuC	TP_0297	TP_0301	Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 22.81; identified by sequence similarity; putative.	Conserved hypothetical integral membrane protein; Probably part of the ABC transporter complex RfuABCD involved in riboflavin import. Probably responsible for the translocation of the substrate across the membrane.	0.530
TP_0297	rfuD	TP_0297	TP_0302	Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 22.81; identified by sequence similarity; putative.	Conserved hypothetical integral membrane protein; Probably part of the ABC transporter complex RfuABCD involved in riboflavin import. Probably responsible for the translocation of the substrate across the membrane.	0.711
TP_0299	TP_0297	TP_0299	TP_0297	Predicted coding region TP0299; Hypothetical protein; identified by Glimmer; putative.	Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 22.81; identified by sequence similarity; putative.	0.727
TP_0299	coaE	TP_0299	TP_0296	Predicted coding region TP0299; Hypothetical protein; identified by Glimmer; putative.	Conserved hypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.	0.490
TP_0299	rfuA	TP_0299	TP_0298	Predicted coding region TP0299; Hypothetical protein; identified by Glimmer; putative.	Exported protein (tpn38b); Probably part of the ABC transporter complex RfuABCD involved in riboflavin import. Binds riboflavin.	0.845
TP_0299	rfuB	TP_0299	TP_0300	Predicted coding region TP0299; Hypothetical protein; identified by Glimmer; putative.	Ribose/galactose ABC transporter, ATP-binding protein (rbsA-1); Probably part of the ABC transporter complex RfuABCD involved in riboflavin import. Probably responsible for energy coupling to the transport system.	0.884
TP_0299	rfuC	TP_0299	TP_0301	Predicted coding region TP0299; Hypothetical protein; identified by Glimmer; putative.	Conserved hypothetical integral membrane protein; Probably part of the ABC transporter complex RfuABCD involved in riboflavin import. Probably responsible for the translocation of the substrate across the membrane.	0.863
TP_0299	rfuD	TP_0299	TP_0302	Predicted coding region TP0299; Hypothetical protein; identified by Glimmer; putative.	Conserved hypothetical integral membrane protein; Probably part of the ABC transporter complex RfuABCD involved in riboflavin import. Probably responsible for the translocation of the substrate across the membrane.	0.884
coaE	TP_0297	TP_0296	TP_0297	Conserved hypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.	Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 22.81; identified by sequence similarity; putative.	0.857
coaE	TP_0299	TP_0296	TP_0299	Conserved hypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.	Predicted coding region TP0299; Hypothetical protein; identified by Glimmer; putative.	0.490
coaE	rfuA	TP_0296	TP_0298	Conserved hypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.	Exported protein (tpn38b); Probably part of the ABC transporter complex RfuABCD involved in riboflavin import. Binds riboflavin.	0.490
coaE	rfuB	TP_0296	TP_0300	Conserved hypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.	Ribose/galactose ABC transporter, ATP-binding protein (rbsA-1); Probably part of the ABC transporter complex RfuABCD involved in riboflavin import. Probably responsible for energy coupling to the transport system.	0.490
coaE	rfuC	TP_0296	TP_0301	Conserved hypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.	Conserved hypothetical integral membrane protein; Probably part of the ABC transporter complex RfuABCD involved in riboflavin import. Probably responsible for the translocation of the substrate across the membrane.	0.490
coaE	rfuD	TP_0296	TP_0302	Conserved hypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.	Conserved hypothetical integral membrane protein; Probably part of the ABC transporter complex RfuABCD involved in riboflavin import. Probably responsible for the translocation of the substrate across the membrane.	0.490
rfuA	TP_0297	TP_0298	TP_0297	Exported protein (tpn38b); Probably part of the ABC transporter complex RfuABCD involved in riboflavin import. Binds riboflavin.	Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 22.81; identified by sequence similarity; putative.	0.626
rfuA	TP_0299	TP_0298	TP_0299	Exported protein (tpn38b); Probably part of the ABC transporter complex RfuABCD involved in riboflavin import. Binds riboflavin.	Predicted coding region TP0299; Hypothetical protein; identified by Glimmer; putative.	0.845