STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rfuCConserved hypothetical integral membrane protein; Probably part of the ABC transporter complex RfuABCD involved in riboflavin import. Probably responsible for the translocation of the substrate across the membrane. (377 aa)    
Predicted Functional Partners:
rfuB
Ribose/galactose ABC transporter, ATP-binding protein (rbsA-1); Probably part of the ABC transporter complex RfuABCD involved in riboflavin import. Probably responsible for energy coupling to the transport system.
 
 
 0.999
rfuD
Conserved hypothetical integral membrane protein; Probably part of the ABC transporter complex RfuABCD involved in riboflavin import. Probably responsible for the translocation of the substrate across the membrane.
 
 
 0.999
rfuA
Exported protein (tpn38b); Probably part of the ABC transporter complex RfuABCD involved in riboflavin import. Binds riboflavin.
 
 
 0.998
TP_0323
Ribose/galactose ABC transporter, permease protein (rbsC-2); Similar to GB:AE000783 percent identity: 32.47; identified by sequence similarity; putative; Belongs to the binding-protein-dependent transport system permease family.
 
 
  0.993
TP_0321
Ribose/galactose ABC transporter, ATP-binding protein (rbsA-2); Similar to GB:AE000783 percent identity: 39.48; identified by sequence similarity; putative.
 
 
 0.974
tmpC
Membrane lipoprotein (tmpC); Binds purine nucleosides and may play a role in purine nucleoside uptake. May be part of an ABC-type nucleoside uptake system. Has highest affinity for guanosine, followed by inosine and adenosine. Has very low affinity for cytidine and does not bind thymidine. Belongs to the BMP lipoprotein family.
 
 
 0.969
TP_0299
Predicted coding region TP0299; Hypothetical protein; identified by Glimmer; putative.
     
 0.880
TP_0322
Ribose/galactose ABC transporter, permease protein (rbsC-1); Similar to GB:AE000783 percent identity: 29.58; identified by sequence similarity; putative; Belongs to the binding-protein-dependent transport system permease family.
  
  
 
0.716
TP_0297
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 22.81; identified by sequence similarity; putative.
     
 0.538
coaE
Conserved hypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
       0.490
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.