STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0307Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 21.80; identified by sequence similarity; putative. (342 aa)    
Predicted Functional Partners:
TP_0308
Amino acid ABC transporter, periplasmic binding protein (hisJ); Similar to GB:J01805 SP:P02910 GB:V01372 GB:V01373 GB:X52093 percent identity: 24.37; identified by sequence similarity; putative.
 
    0.805
TP_0333
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 31.40; identified by sequence similarity; putative.
 
   
 0.768
ftsQ
Cell division protein (ftsQ); Essential cell division protein.
 
  
 0.737
TP_0739
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 25.32; identified by sequence similarity; putative.
  
     0.679
pbp1
Penicillin-binding protein (pbp-1); Similar to GB:AE000783 percent identity: 37.14; identified by sequence similarity; putative.
 
  
 0.672
pbp2
Penicillin-binding protein (pbp-3); Similar to GB:AE000783 percent identity: 30.81; identified by sequence similarity; putative.
 
  
 0.670
dacC
Serine-type D-Ala-D-Ala carboxypeptidase (dacC); Similar to GB:AE000783 percent identity: 30.68; identified by sequence similarity; putative; Belongs to the peptidase S11 family.
     
 0.670
murF
UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanine ligase (murF); Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
  
 
 0.654
TP_0408
Predicted coding region TP0408; Hypothetical protein; identified by Glimmer; putative.
  
    0.646
TP_0990
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 23.34; identified by sequence similarity; putative.
  
     0.646
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.