STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TP_0308Amino acid ABC transporter, periplasmic binding protein (hisJ); Similar to GB:J01805 SP:P02910 GB:V01372 GB:V01373 GB:X52093 percent identity: 24.37; identified by sequence similarity; putative. (321 aa)    
Predicted Functional Partners:
TP_0309
Amino acid ABC transporter, periplasmic binding protein; Similar to SP:P42199 PID:666981 GB:AL009126 percent identity: 25.87; identified by sequence similarity; putative.
 
  
0.970
cheW1
Purine-binding chemotaxis protein (cheW-1); Similar to GP:1765974 percent identity: 99.78; identified by sequence similarity; putative.
    
 0.924
TP_0307
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 21.80; identified by sequence similarity; putative.
 
    0.805
rpsD
Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
 
     0.596
ssb2
Predicted coding region TP0310; Hypothetical protein; identified by Glimmer; putative.
       0.580
TP_0519
Response regulatory protein (atoC); Similar to GB:AE000783 percent identity: 54.34; identified by sequence similarity; putative.
    
 0.573
TP_0223
Aspartate aminotransferase (tpaaT); Similar to GP:2104501 percent identity: 99.77; identified by sequence similarity; putative.
 
  
 0.552
cheA
Chemotaxis histidine kinase (cheA); Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY (By similarity).
    
  0.509
TP_0939
Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative.
  
 
 0.508
TP_0312
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 28.69; identified by sequence similarity; putative.
     
 0.474
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.