STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TP_0309Amino acid ABC transporter, periplasmic binding protein; Similar to SP:P42199 PID:666981 GB:AL009126 percent identity: 25.87; identified by sequence similarity; putative. (272 aa)    
Predicted Functional Partners:
TP_0308
Amino acid ABC transporter, periplasmic binding protein (hisJ); Similar to GB:J01805 SP:P02910 GB:V01372 GB:V01373 GB:X52093 percent identity: 24.37; identified by sequence similarity; putative.
 
  
0.970
cheW1
Purine-binding chemotaxis protein (cheW-1); Similar to GP:1765974 percent identity: 99.78; identified by sequence similarity; putative.
    
 0.924
ssb2
Predicted coding region TP0310; Hypothetical protein; identified by Glimmer; putative.
       0.773
TP_0307
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 21.80; identified by sequence similarity; putative.
 
    0.638
TP_0312
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 28.69; identified by sequence similarity; putative.
     
 0.576
TP_0519
Response regulatory protein (atoC); Similar to GB:AE000783 percent identity: 54.34; identified by sequence similarity; putative.
    
 0.573
cheA
Chemotaxis histidine kinase (cheA); Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY (By similarity).
    
  0.509
TP_0939
Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative.
  
 
 0.508
TP_0223
Aspartate aminotransferase (tpaaT); Similar to GP:2104501 percent identity: 99.77; identified by sequence similarity; putative.
    
 0.490
fliY
Flagellar motor switch protein (fliY); FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.
    
 
 0.471
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.