STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TP_0330Cell division protein, putative; Similar to GB:L43967 SP:P47695 PID:1046176 percent identity: 29.18; identified by sequence similarity; putative. (598 aa)    
Predicted Functional Partners:
htpG
Heat shock protein 90 (htpG); Molecular chaperone. Has ATPase activity.
   
 0.916
dnaK
Heat shock protein 70 (dnaK); Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.890
TP_0502
Predicted coding region TP0502; Hypothetical protein; identified by Glimmer; putative.
  
 
 0.858
TP_0835
Ankyrin, putative; Similar to GB:X56958 SP:Q01485 PID:29491 percent identity: 30.66; identified by sequence similarity; putative.
  
 
 0.849
TP_0100
Thioredoxin, putative; Similar to GB:Z23140 SP:P43221 PID:312981 percent identity: 33.05; identified by sequence similarity; putative.
  
 0.822
TP_0098
Heat-shock protein, putative; Similar to PID:1046215 SP:P50025 percent identity: 45.69; identified by sequence similarity; putative.
   
 0.821
TP_0563
Predicted coding region TP0563; Hypothetical protein; identified by Glimmer; putative.
   
 0.821
dnaN
DNA polymerase III, subunit beta (dnaN); Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initia [...]
    
 0.807
ndk
Nucleoside-diphosphate kinase (ndk); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
 
 0.806
recA
recA protein (recA); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
   
 0.798
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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