| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| TP_0223 | glyA | TP_0223 | TP_0329 | Aspartate aminotransferase (tpaaT); Similar to GP:2104501 percent identity: 99.77; identified by sequence similarity; putative. | Serine hydroxymethyltransferase (glyA); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.682 |
| TP_0223 | metG | TP_0223 | TP_0798 | Aspartate aminotransferase (tpaaT); Similar to GP:2104501 percent identity: 99.77; identified by sequence similarity; putative. | methionyl-tRNA synthetase (metG); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.568 |
| TP_0223 | proA | TP_0223 | TP_0350 | Aspartate aminotransferase (tpaaT); Similar to GP:2104501 percent identity: 99.77; identified by sequence similarity; putative. | Glutamate-5-semialdehyde dehydrogenase (proA); Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.507 |
| TP_0223 | proB | TP_0223 | TP_0351 | Aspartate aminotransferase (tpaaT); Similar to GP:2104501 percent identity: 99.77; identified by sequence similarity; putative. | Glutamate 5-kinase (proB); Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.553 |
| fliY | proB | TP_0720 | TP_0351 | Flagellar motor switch protein (fliY); FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family. | Glutamate 5-kinase (proB); Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.565 |
| glyA | TP_0223 | TP_0329 | TP_0223 | Serine hydroxymethyltransferase (glyA); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Aspartate aminotransferase (tpaaT); Similar to GP:2104501 percent identity: 99.77; identified by sequence similarity; putative. | 0.682 |
| glyA | lon | TP_0329 | TP_0524 | Serine hydroxymethyltransferase (glyA); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | ATP-dependent protease LA (lon-2); ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.787 |
| glyA | metG | TP_0329 | TP_0798 | Serine hydroxymethyltransferase (glyA); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | methionyl-tRNA synthetase (metG); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.748 |
| glyA | proA | TP_0329 | TP_0350 | Serine hydroxymethyltransferase (glyA); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Glutamate-5-semialdehyde dehydrogenase (proA); Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.907 |
| glyA | proB | TP_0329 | TP_0351 | Serine hydroxymethyltransferase (glyA); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Glutamate 5-kinase (proB); Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.578 |
| glyA | proC | TP_0329 | TP_0797 | Serine hydroxymethyltransferase (glyA); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 1-pyrroline-5-carboxylate reductase (proC); Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.514 |
| lon | glyA | TP_0524 | TP_0329 | ATP-dependent protease LA (lon-2); ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | Serine hydroxymethyltransferase (glyA); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.787 |
| lon | prfB | TP_0524 | TP_0576 | ATP-dependent protease LA (lon-2); ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | Peptide chain release factor 2 (prfB); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | 0.437 |
| lon | proA | TP_0524 | TP_0350 | ATP-dependent protease LA (lon-2); ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | Glutamate-5-semialdehyde dehydrogenase (proA); Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.747 |
| lon | proB | TP_0524 | TP_0351 | ATP-dependent protease LA (lon-2); ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | Glutamate 5-kinase (proB); Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.723 |
| metG | TP_0223 | TP_0798 | TP_0223 | methionyl-tRNA synthetase (metG); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Aspartate aminotransferase (tpaaT); Similar to GP:2104501 percent identity: 99.77; identified by sequence similarity; putative. | 0.568 |
| metG | glyA | TP_0798 | TP_0329 | methionyl-tRNA synthetase (metG); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Serine hydroxymethyltransferase (glyA); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.748 |
| metG | prfB | TP_0798 | TP_0576 | methionyl-tRNA synthetase (metG); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Peptide chain release factor 2 (prfB); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | 0.662 |
| metG | proA | TP_0798 | TP_0350 | methionyl-tRNA synthetase (metG); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Glutamate-5-semialdehyde dehydrogenase (proA); Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.589 |
| metG | proB | TP_0798 | TP_0351 | methionyl-tRNA synthetase (metG); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Glutamate 5-kinase (proB); Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.557 |
