STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0361Lysophosphatidic acid acyltransferase, putative; Similar to GP:2286207 percent identity: 35.20; identified by sequence similarity; putative. (282 aa)    
Predicted Functional Partners:
gpsA
Glycerol-3-phosphate dehydrogenase (gpsA); Similar to SP:P46919 PID:974332 PID:1146220 GB:AL009126 percent identity: 35.44; identified by sequence similarity; putative; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
    
 0.965
cdsA
Phosphatidate cytidylyltransferase (cdsA); Similar to GB:AE000783 percent identity: 32.47; identified by sequence similarity; putative.
    
 0.964
plsC
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 33.85; identified by sequence similarity; putative.
     
 0.946
acpP
Acyl carrier protein (acpP); Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
  
 0.828
fadD1
long-chain-fatty-acid--CoA ligase; Similar to GB:AE000783 percent identity: 39.55; identified by sequence similarity; putative.
    
 0.791
TP_0551
Phosphatase; Similar to GB:L25421 PID:409159 percent identity: 32.50; identified by sequence similarity; putative.
   
 0.780
TP_1033
Conserved hypothetical protein; Similar to GB:AL009126 percent identity: 30.74; identified by sequence similarity; putative.
    
  0.723
dnaK
Heat shock protein 70 (dnaK); Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.713
ispDF
Conserved hypothetical protein; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF); In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
  
  
 0.707
dctD
Deoxycytidylate deaminase, putative; Similar to GB:AE000782 percent identity: 47.95; identified by sequence similarity; putative.
    
  0.697
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.