STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
TP_0369Predicted coding region TP0369; Hypothetical protein; identified by Glimmer; putative. (516 aa)    
Predicted Functional Partners:
smc
Chromosome segregation protein, putative; Required for chromosome condensation and partitioning. Belongs to the SMC family.
       0.823
fliO
Hypothetical protein; Similar to PID:1216382 PID:973196 percent identity: 100.00; identified by sequence similarity; putative.
  
  
  0.819
TP_0438
Conserved hypothetical protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
   
   0.813
TP_0622
Predicted coding region TP0622; Hypothetical protein; identified by Glimmer; putative.
 
     0.789
TP_0368
Predicted coding region TP0368; Hypothetical protein; identified by Glimmer; putative.
       0.781
TP_0408
Predicted coding region TP0408; Hypothetical protein; identified by Glimmer; putative.
 
     0.774
TP_0304
Predicted coding region TP0304; Hypothetical protein; identified by Glimmer; putative.
 
   
 0.773
TP_0481
Predicted coding region TP0481; Hypothetical protein; identified by Glimmer; putative.
  
     0.770
TP_0990
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 23.34; identified by sequence similarity; putative.
  
     0.767
TP_0095
Predicted coding region TP0095; Hypothetical protein; identified by Glimmer; putative.
  
     0.763
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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