STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0381Predicted coding region TP0381; Hypothetical protein; identified by Glimmer; putative. (238 aa)    
Predicted Functional Partners:
fadD1
long-chain-fatty-acid--CoA ligase; Similar to GB:AE000783 percent identity: 39.55; identified by sequence similarity; putative.
      
 0.613
TP_0986
Conserved hypothetical integral membrane protein; Similar to GB:AE000511 PID:2314395 percent identity: 30.69; identified by sequence similarity; putative.
      
 0.613
murF
UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanine ligase (murF); Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
       0.596
TP_0382
Predicted coding region TP0382; Hypothetical protein; identified by Glimmer; putative.
       0.550
mraZ
Conserved hypothetical protein; Similar to GP:2624082 percent identity: 33.56; identified by sequence similarity; putative; Belongs to the MraZ family.
       0.491
rsmH
Conserved hypothetical protein; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
       0.491
TP_0380
DNA repair helicase, putative; Similar to GB:Z47047 SP:Q00578 PID:172327 PID:172724 PID:557780 percent identity: 32.92; identified by sequence similarity; putative.
       0.487
TP_0385
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 31.43; identified by sequence similarity; putative.
       0.476
ftsW
Cell division protein (ftsW); Similar to PID:1165286 SP:Q44775 PID:1223601 PID:1223610 PID:1234873 percent identity: 34.57; identified by sequence similarity; putative; Belongs to the SEDS family.
       0.476
ftsQ
Cell division protein (ftsQ); Essential cell division protein.
       0.476
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.