STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0405mcbG protein, putative; Similar to SP:P05530 GB:X07875 PID:41983 percent identity: 23.94; identified by sequence similarity; putative. (149 aa)    
Predicted Functional Partners:
TP_0404
Predicted coding region TP0404; Hypothetical protein; identified by Glimmer; putative.
       0.853
TP_0623
Membrane-bound lytic murein transglycosylase D (dniR); Similar to SP:P23931 GB:X60739 PID:1208972 PID:581068 GB:U00096 percent identity: 32.28; identified by sequence similarity; putative.
   
 
 0.625
TP_0986
Conserved hypothetical integral membrane protein; Similar to GB:AE000511 PID:2314395 percent identity: 30.69; identified by sequence similarity; putative.
   
   0.577
TP_0522
Predicted coding region TP0522; Hypothetical protein; identified by Glimmer; putative.
  
   
 0.567
murI
Glutamate racemase (murI); Provides the (R)-glutamate required for cell wall biosynthesis.
       0.566
TP_1029
Predicted coding region TP1029; Hypothetical protein; identified by Glimmer; putative.
 
 
   0.555
nrdA
Ribonucleoside-diphosphate reductase, subunit alpha (nrdA); Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).
    
  0.527
TP_0408
Predicted coding region TP0408; Hypothetical protein; identified by Glimmer; putative.
 
     0.518
fusA
Translation elongation factor G (fusA-2); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor G [...]
 
 
   0.518
mazG
mazG protein (mazG); Similar to GB:J04039 SP:P33646 PID:416198 PID:882675 GB:U00096 percent identity: 37.45; identified by sequence similarity; putative.
    
  0.480
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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