STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0408Predicted coding region TP0408; Hypothetical protein; identified by Glimmer; putative. (1084 aa)    
Predicted Functional Partners:
cheW1
Purine-binding chemotaxis protein (cheW-1); Similar to GP:1765974 percent identity: 99.78; identified by sequence similarity; putative.
 
  
 0.937
TP_0486
Antigen, p83/100; Similar to PID:928980 PID:928982 PID:928985 PID:1272517 GB:AE000783 percent identity: 26.14; identified by sequence similarity; putative.
 
  
 0.882
TP_0261
Catabolite gene activator, putative; Similar to PID:1653345 percent identity: 30.99; identified by sequence similarity; putative.
 
 
 0.843
scpA
Conserved hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
  
 
 0.810
gyrB
DNA gyrase, subunit B (gyrB); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.801
TP_0920
Predicted coding region TP0920; Hypothetical protein; identified by Glimmer; putative.
 
   
 0.787
TP_0996
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 30.00; identified by sequence similarity; putative.
  
 
   0.781
ftsQ
Cell division protein (ftsQ); Essential cell division protein.
 
     0.778
TP_0990
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 23.34; identified by sequence similarity; putative.
 
     0.775
TP_0095
Predicted coding region TP0095; Hypothetical protein; identified by Glimmer; putative.
 
     0.774
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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