STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TP_0421Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 27.26; identified by sequence similarity; putative. (683 aa)    
Predicted Functional Partners:
TP_0567
Conserved hypothetical protein; Similar to PID:1165270 PID:1196323 GB:AE000783 percent identity: 30.48; identified by sequence similarity; putative.
  
 
   0.933
TP_0544
Predicted coding region TP0544; Hypothetical protein; identified by Glimmer; putative.
    
 0.805
surE
Survival protein, putative; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
  0.785
TP_0333
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 31.40; identified by sequence similarity; putative.
  
   
 0.783
TP_0285
Predicted coding region TP0285; Hypothetical protein; identified by Glimmer; putative.
 
    0.780
TP_0422
Predicted coding region TP0422; Hypothetical protein; identified by Glimmer; putative.
       0.773
TP_0408
Predicted coding region TP0408; Hypothetical protein; identified by Glimmer; putative.
 
     0.750
TP_0486
Antigen, p83/100; Similar to PID:928980 PID:928982 PID:928985 PID:1272517 GB:AE000783 percent identity: 26.14; identified by sequence similarity; putative.
  
     0.749
TP_0263
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 24.22; identified by sequence similarity; putative.
  
     0.744
TP_0990
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 23.34; identified by sequence similarity; putative.
  
     0.740
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.