STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0422Predicted coding region TP0422; Hypothetical protein; identified by Glimmer; putative. (341 aa)    
Predicted Functional Partners:
TP_0421
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 27.26; identified by sequence similarity; putative.
       0.773
TP_0423
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 39.66; identified by sequence similarity; putative.
       0.693
galK
Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.
       0.489
surE
Survival protein, putative; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
       0.489
TP_0420
Predicted coding region TP0420; Hypothetical protein; identified by Glimmer; putative.
       0.489
atpE
V-type ATPase, subunit E, putative; Produces ATP from ADP in the presence of a proton gradient across the membrane.
       0.404
TP_0425
Predicted coding region TP0425; Hypothetical protein; identified by Glimmer; putative.
       0.404
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.