STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TP_0423Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 39.66; identified by sequence similarity; putative. (268 aa)    
Predicted Functional Partners:
TP_0421
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 27.26; identified by sequence similarity; putative.
       0.694
TP_0422
Predicted coding region TP0422; Hypothetical protein; identified by Glimmer; putative.
       0.693
surE
Survival protein, putative; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
 
     0.541
wecG
UDP-N-acetyl-D-mannosamine transferase, putative; Similar to GB:U09239 PID:485280 percent identity: 22.22; identified by sequence similarity; putative.
  
     0.533
TP_0307
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 21.80; identified by sequence similarity; putative.
 
    0.514
upp
Uracil phosphoribosyltransferase, putative; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
 
    0.464
galK
Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.
  
    0.448
cmk
Ribosomal protein S1 (rpsA); Similar to SP:P02349 GB:V00342 GB:V00352 GB:X04864 PID:42837 percent identity: 36.77; identified by sequence similarity; putative.
  
    0.446
TP_0420
Predicted coding region TP0420; Hypothetical protein; identified by Glimmer; putative.
       0.445
rpsF
Ribosomal protein S6 (rpsF); Binds together with S18 to 16S ribosomal RNA.
  
     0.444
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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