STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
coaXConserved hypothetical protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. (273 aa)    
Predicted Functional Partners:
coaD
Lipopolysaccharide core biosynthesis protein (kdtB); Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
 
  
 0.964
mazG
mazG protein (mazG); Similar to GB:J04039 SP:P33646 PID:416198 PID:882675 GB:U00096 percent identity: 37.45; identified by sequence similarity; putative.
   
 
  0.926
tmk
Thymidylate kinase (tmk); Similar to GB:L77117 SP:Q57741 PID:1591015 percent identity: 35.14; identified by sequence similarity; putative.
   
   0.890
cmk
Ribosomal protein S1 (rpsA); Similar to SP:P02349 GB:V00342 GB:V00352 GB:X04864 PID:42837 percent identity: 36.77; identified by sequence similarity; putative.
    
 0.677
birA
biotin--acetyl-CoA-carboxylase ligase (birA); Similar to GP:1877334 percent identity: 28.89; identified by sequence similarity; putative.
 
    0.665
ntpK
V-type ATPase, subunit K (atpK-1); Similar to GB:AE000783 percent identity: 53.96; identified by sequence similarity; putative.
       0.664
TP_0432
Predicted coding region TP0432; Hypothetical protein; identified by Glimmer; putative.
       0.634
atpD1
V-type ATPase, subunit D (atpD-1); Produces ATP from ADP in the presence of a proton gradient across the membrane.
       0.560
atpI1
V-type ATPase, subunit I (atpI-1); Produces ATP from ADP in the presence of a proton gradient across the membrane; Belongs to the V-ATPase 116 kDa subunit family.
       0.560
atpA1
V-type ATPase, subunit A (atpA-1); Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity); Belongs to the ATPase alpha/beta chains family.
       0.546
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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