STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0461Predicted coding region TP0461; Hypothetical protein; identified by Glimmer; putative. (119 aa)    
Predicted Functional Partners:
TP_0939
Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative.
  
 
 0.953
nadE
NH(3)-dependent NAD(+) synthetase (nadE); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.
    
 0.941
TP_0261
Catabolite gene activator, putative; Similar to PID:1653345 percent identity: 30.99; identified by sequence similarity; putative.
     
 0.834
TP_0460
Predicted coding region TP0460; Hypothetical protein; identified by Glimmer; putative.
       0.773
TP_0468
Conserved hypothetical protein; Similar to GB:AL009126 percent identity: 28.43; identified by sequence similarity; putative.
     
 0.763
ptsN
PTS system, nitrogen regulatory IIA component (ptsN-2); Similar to GB:D12938 SP:P31222 GB:Z27094 PID:285783 PID:414887 percent identity: 29.86; identified by sequence similarity; putative.
  
 
 0.759
alr
Alanine racemase (alr); Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
    
 0.679
rluB
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 36.68; identified by sequence similarity; putative; Belongs to the pseudouridine synthase RsuA family.
  
    0.644
nrdA
Ribonucleoside-diphosphate reductase, subunit alpha (nrdA); Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).
     
 0.640
murB
UDP-N-acetylmuramate dehydrogenase (murB); Cell wall formation.
    
 0.636
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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