STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0471Predicted coding region TP0471; Hypothetical protein; identified by Glimmer; putative. (469 aa)    
Predicted Functional Partners:
TP_0468
Conserved hypothetical protein; Similar to GB:AL009126 percent identity: 28.43; identified by sequence similarity; putative.
 
  
  0.945
TP_0469
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 27.17; identified by sequence similarity; putative.
 
     0.887
TP_0470
Conserved hypothetical protein; Similar to PID:1001414 PID:1001426 percent identity: 27.91; identified by sequence similarity; putative.
 
  
  0.865
TP_0067
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 47.91; identified by sequence similarity; putative.
 
  
  0.772
TP_0268
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 28.74; identified by sequence similarity; putative.
 
  
  0.751
TP_0460
Predicted coding region TP0460; Hypothetical protein; identified by Glimmer; putative.
  
     0.747
TP_0954
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 24.29; identified by sequence similarity; putative.
 
  
  0.736
polA
DNA polymerase I (polA); In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
    0.700
TP_0261
Catabolite gene activator, putative; Similar to PID:1653345 percent identity: 30.99; identified by sequence similarity; putative.
 
  
  0.692
TP_0648
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 22.78; identified by sequence similarity; putative.
 
     0.687
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.