STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0494Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 33.47; identified by sequence similarity; putative. (273 aa)    
Predicted Functional Partners:
dnaG
DNA primase (dnaG); RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
     
 0.851
rpoD
RNA polymerase sigma-70 factor (rpoD); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
     
 0.838
rnhA
Ribonuclease H (rnhA); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
  
  
 0.796
TP_0489
Conserved hypothetical protein; Similar to PID:1651839 percent identity: 44.36; identified by sequence similarity; putative.
  
    0.776
mltG
Conserved hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.
       0.770
TP_0050
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 41.88; identified by sequence similarity; putative.
  
   
 0.713
TP_0490
Conserved hypothetical protein; Similar to GP:1483540 percent identity: 33.93; identified by sequence similarity; putative.
       0.687
cmk
Ribosomal protein S1 (rpsA); Similar to SP:P02349 GB:V00342 GB:V00352 GB:X04864 PID:42837 percent identity: 36.77; identified by sequence similarity; putative.
 
     0.597
TP_0977
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 44.30; identified by sequence similarity; putative.
  
  
 0.591
rpoN
RNA polymerase sigma-54 factor (rpoN); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
    
 
 0.584
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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