STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pbp1Penicillin-binding protein (pbp-1); Similar to GB:AE000783 percent identity: 37.14; identified by sequence similarity; putative. (624 aa)    
Predicted Functional Partners:
rodA
Rod shape-determining protein (rodA); Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
 
 0.999
mreB
Rod shape-determining protein (mreB); Similar to GB:AE000783 percent identity: 62.72; identified by sequence similarity; putative.
 
 
 
 0.978
mreC
Rod shape-determining protein (mreC); Involved in formation and maintenance of cell shape.
 
 
 0.975
ftsW
Cell division protein (ftsW); Similar to PID:1165286 SP:Q44775 PID:1223601 PID:1223610 PID:1234873 percent identity: 34.57; identified by sequence similarity; putative; Belongs to the SEDS family.
 
 0.974
ftsQ
Cell division protein (ftsQ); Essential cell division protein.
  
 
 0.952
pbp2
Penicillin-binding protein (pbp-3); Similar to GB:AE000783 percent identity: 30.81; identified by sequence similarity; putative.
  
  
0.951
mreD
Rod shape-determining protein (mreD); Similar to GB:M31792 SP:P16927 PID:146819 PID:606189 GB:U00096 percent identity: 24.84; identified by sequence similarity; putative.
  
  
 0.882
mrcA
Penicillin-binding protein (pbp-2); Similar to GB:AE000783 percent identity: 40.76; identified by sequence similarity; putative.
 
 
 
 0.875
murE
UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase (murE); Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan; Belongs to the MurCDEF family. MurE subfamily.
  
 0.829
TP_0496
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 29.52; identified by sequence similarity; putative.
 
     0.784
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.