STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
rodARod shape-determining protein (rodA); Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (433 aa)    
Predicted Functional Partners:
pbp1
Penicillin-binding protein (pbp-1); Similar to GB:AE000783 percent identity: 37.14; identified by sequence similarity; putative.
 0.998
mreB
Rod shape-determining protein (mreB); Similar to GB:AE000783 percent identity: 62.72; identified by sequence similarity; putative.
 
 
 
 0.960
pbp2
Penicillin-binding protein (pbp-3); Similar to GB:AE000783 percent identity: 30.81; identified by sequence similarity; putative.
 
 0.948
ftsQ
Cell division protein (ftsQ); Essential cell division protein.
  
 
 0.947
ftsW
Cell division protein (ftsW); Similar to PID:1165286 SP:Q44775 PID:1223601 PID:1223610 PID:1234873 percent identity: 34.57; identified by sequence similarity; putative; Belongs to the SEDS family.
  
  
 
0.943
mreC
Rod shape-determining protein (mreC); Involved in formation and maintenance of cell shape.
 
  
 0.940
murG
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
 
 0.922
mreD
Rod shape-determining protein (mreD); Similar to GB:M31792 SP:P16927 PID:146819 PID:606189 GB:U00096 percent identity: 24.84; identified by sequence similarity; putative.
  
  
 0.903
murC
UDP-N-acetylmuramate--alanine ligase (murC); Cell wall formation; Belongs to the MurCDEF family.
 
  
 0.880
mraY
phospho-N-acetylmuramoyl-pentapeptide- transferase (mraY); First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
 
  
 0.828
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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