STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0515Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 24.85; identified by sequence similarity; putative. (991 aa)    
Predicted Functional Partners:
TP_0785
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 27.37; identified by sequence similarity; putative.
  
 
 0.977
uvrA
Excinuclease ABC, subunit A (uvrA); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
     
 0.839
TP_0786
ABC transporter, ATP-binding protein, putative; Similar to GB:D12938 SP:P31220 PID:285780 PID:551337 PID:606140 percent identity: 52.52; identified by sequence similarity; putative.
  
 
 0.838
TP_0883
Conserved hypothetical integral membrane protein; Similar to GB:AE000783 percent identity: 19.26; identified by sequence similarity; putative.
  
 
 0.742
TP_0884
Conserved hypothetical integral membrane protein; Similar to GB:AE000783 percent identity: 30.66; identified by sequence similarity; putative.
  
 
 0.742
TP_0304
Predicted coding region TP0304; Hypothetical protein; identified by Glimmer; putative.
  
  
 0.672
tp92
Outer membrane protein; Might be part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane; Belongs to the BamA family.
   
  
 0.672
tpn39b
Basic membrane protein (tpn39b); Similar to GB:M17716 SP:P29725 PID:155055 percent identity: 100.00; identified by sequence similarity; putative.
  
  
 0.572
nicO
Conserved hypothetical integral membrane protein; Similar to GB:L42023 SP:P44136 PID:1007168 PID:1221377 PID:1205489 percent identity: 24.48; identified by sequence similarity; putative; Belongs to the NiCoT transporter (TC 2.A.52) family.
     
 0.512
TP_0346
Predicted coding region TP0346; Hypothetical protein; identified by Glimmer; putative.
      
 0.509
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.