STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0522Predicted coding region TP0522; Hypothetical protein; identified by Glimmer; putative. (159 aa)    
Predicted Functional Partners:
murG
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
  
  
 0.874
dnaZX1
DNA polymerase III, gamma and tau subunits, putative; Similar to GB:D26185 SP:P09122 GB:X06803 GB:X17014 PID:467409 percent identity: 33.92; identified by sequence similarity; putative.
 
  
 0.866
lon
ATP-dependent protease LA (lon-2); ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
  
  
 0.844
TP_0990
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 23.34; identified by sequence similarity; putative.
 
    0.801
TP_1002
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 31.50; identified by sequence similarity; putative.
  
     0.761
TP_0846
Predicted coding region TP0846; Hypothetical protein; identified by Glimmer; putative.
  
  
 0.742
TP_0996
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 30.00; identified by sequence similarity; putative.
 
     0.720
TP_0408
Predicted coding region TP0408; Hypothetical protein; identified by Glimmer; putative.
 
     0.714
TP_0995
Cyclic nucleotide binding protein; Similar to PID:1653946 percent identity: 33.90; identified by sequence similarity; putative.
 
     0.710
TP_0592
Predicted coding region TP0592; Hypothetical protein; identified by Glimmer; putative.
  
     0.685
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.