node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
TP_0098 | dnaK | TP_0098 | TP_0216 | Heat-shock protein, putative; Similar to PID:1046215 SP:P50025 percent identity: 45.69; identified by sequence similarity; putative. | Heat shock protein 70 (dnaK); Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.999 |
TP_0098 | ftsH | TP_0098 | TP_0765 | Heat-shock protein, putative; Similar to PID:1046215 SP:P50025 percent identity: 45.69; identified by sequence similarity; putative. | Cell division protein (ftsH); Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | 0.642 |
TP_0098 | groL | TP_0098 | TP_0030 | Heat-shock protein, putative; Similar to PID:1046215 SP:P50025 percent identity: 45.69; identified by sequence similarity; putative. | Heat shock protein (groEL); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family. | 0.902 |
TP_0098 | grpE | TP_0098 | TP_0215 | Heat-shock protein, putative; Similar to PID:1046215 SP:P50025 percent identity: 45.69; identified by sequence similarity; putative. | grpE protein (grpE); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depe [...] | 0.977 |
TP_0098 | htpG | TP_0098 | TP_0984 | Heat-shock protein, putative; Similar to PID:1046215 SP:P50025 percent identity: 45.69; identified by sequence similarity; putative. | Heat shock protein 90 (htpG); Molecular chaperone. Has ATPase activity. | 0.996 |
TP_0098 | lon | TP_0098 | TP_0524 | Heat-shock protein, putative; Similar to PID:1046215 SP:P50025 percent identity: 45.69; identified by sequence similarity; putative. | ATP-dependent protease LA (lon-2); ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.786 |
TP_0522 | dnaK | TP_0522 | TP_0216 | Predicted coding region TP0522; Hypothetical protein; identified by Glimmer; putative. | Heat shock protein 70 (dnaK); Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.497 |
TP_0522 | dnaZX1 | TP_0522 | TP_0521 | Predicted coding region TP0522; Hypothetical protein; identified by Glimmer; putative. | DNA polymerase III, gamma and tau subunits, putative; Similar to GB:D26185 SP:P09122 GB:X06803 GB:X17014 PID:467409 percent identity: 33.92; identified by sequence similarity; putative. | 0.866 |
TP_0522 | lon | TP_0522 | TP_0524 | Predicted coding region TP0522; Hypothetical protein; identified by Glimmer; putative. | ATP-dependent protease LA (lon-2); ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.844 |
TP_0563 | dnaK | TP_0563 | TP_0216 | Predicted coding region TP0563; Hypothetical protein; identified by Glimmer; putative. | Heat shock protein 70 (dnaK); Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.999 |
TP_0563 | ftsH | TP_0563 | TP_0765 | Predicted coding region TP0563; Hypothetical protein; identified by Glimmer; putative. | Cell division protein (ftsH); Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | 0.592 |
TP_0563 | groL | TP_0563 | TP_0030 | Predicted coding region TP0563; Hypothetical protein; identified by Glimmer; putative. | Heat shock protein (groEL); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family. | 0.902 |
TP_0563 | grpE | TP_0563 | TP_0215 | Predicted coding region TP0563; Hypothetical protein; identified by Glimmer; putative. | grpE protein (grpE); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depe [...] | 0.945 |
TP_0563 | htpG | TP_0563 | TP_0984 | Predicted coding region TP0563; Hypothetical protein; identified by Glimmer; putative. | Heat shock protein 90 (htpG); Molecular chaperone. Has ATPase activity. | 0.998 |
TP_0563 | lon | TP_0563 | TP_0524 | Predicted coding region TP0563; Hypothetical protein; identified by Glimmer; putative. | ATP-dependent protease LA (lon-2); ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.786 |
clpX | dnaK | TP_0508 | TP_0216 | ATP-dependent Clp protease subunit X (clpX); ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | Heat shock protein 70 (dnaK); Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.555 |
clpX | ftsH | TP_0508 | TP_0765 | ATP-dependent Clp protease subunit X (clpX); ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | Cell division protein (ftsH); Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | 0.907 |
clpX | groL | TP_0508 | TP_0030 | ATP-dependent Clp protease subunit X (clpX); ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | Heat shock protein (groEL); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family. | 0.538 |
clpX | grpE | TP_0508 | TP_0215 | ATP-dependent Clp protease subunit X (clpX); ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | grpE protein (grpE); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depe [...] | 0.582 |
clpX | htpG | TP_0508 | TP_0984 | ATP-dependent Clp protease subunit X (clpX); ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | Heat shock protein 90 (htpG); Molecular chaperone. Has ATPase activity. | 0.456 |