STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
TP_0544Predicted coding region TP0544; Hypothetical protein; identified by Glimmer; putative. (622 aa)    
Predicted Functional Partners:
TP_0104
5'-nucleotidase (ushA); Similar to GB:L42023 SP:P44569 PID:1003311 PID:1222124 PID:1204463 percent identity: 50.63; identified by sequence similarity; putative.
  
 0.966
TP_0421
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 27.26; identified by sequence similarity; putative.
    
 0.805
TP_0667
Uridine kinase (udk); Similar to SP:Q59190 PID:1405442 GB:AE000783 percent identity: 28.33; identified by sequence similarity; putative.
    
  0.715
deoD
Purine nucleoside phosphorylase (deoD); Similar to GP:1638807 percent identity: 57.51; identified by sequence similarity; putative.
    
  0.715
TP_0545
Methylgalactoside ABC transporter, periplasmic galactose-binding protein (mglB-1); Similar to SP:P23925 GB:X59389 PID:40473 percent identity: 37.27; identified by sequence similarity; putative.
  
    0.703
upp
Uracil phosphoribosyltransferase, putative; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
    
  0.697
pyrH
Uridylate kinase (smbA); Catalyzes the reversible phosphorylation of UMP to UDP.
    
  0.691
adk
Adenylate kinase (adk); Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
    
  0.691
apt
Adenine phosphoribosyltransferase (apt); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
    
  0.691
add
Adenosine deaminase, putative; Putative nucleoside deaminase. May catalyze the hydrolytic deamination of adenosine or some similar substrate and play a role in purine metabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
     
  0.690
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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