STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TP_0551Phosphatase; Similar to GB:L25421 PID:409159 percent identity: 32.50; identified by sequence similarity; putative. (362 aa)    
Predicted Functional Partners:
rplF
Ribosomal protein L6 (rplF); This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
   
  0.882
glpQ
Glycerophosphoryldiester phosphodiesterase (glpQ); Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to G3P and the corresponding alcohols.
  
 0.811
TP_0534
Predicted coding region TP0534; Hypothetical protein; identified by Glimmer; putative.
    
   0.798
mnmE
Thiophene and furan oxidation protein (thdF); Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
       0.797
TP_0531
V-type ATPase, subunit F, putative; Similar to PID:1199637 SP:Q60185 percent identity: 31.63; identified by sequence similarity; putative.
  
 
   0.783
TP_0361
Lysophosphatidic acid acyltransferase, putative; Similar to GP:2286207 percent identity: 35.20; identified by sequence similarity; putative.
   
 0.780
mraY
phospho-N-acetylmuramoyl-pentapeptide- transferase (mraY); First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
 
  
 0.777
TP_0552
Predicted coding region TP0552; Hypothetical protein; identified by Glimmer; putative.
       0.757
TP_0290
Conserved hypothetical protein; Similar to GP:1418999 percent identity: 27.07; identified by sequence similarity; putative.
    
 0.751
ribF
Riboflavin kinase/FMN adenylyltransferase (ribF); Similar to GB:U00096 PID:1786208 percent identity: 31.05; identified by sequence similarity; putative.
 
  
  0.732
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.