STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0553Conserved hypothetical integral membrane protein; Similar to GB:AE000511 PID:2313674 percent identity: 27.87; identified by sequence similarity; putative. (403 aa)    
Predicted Functional Partners:
gph
Phosphoglycolate phosphatase (gph-2); Similar to GB:L42023 SP:P44755 PID:1004013 PID:1222502 PID:1204815 percent identity: 32.55; identified by sequence similarity; putative.
       0.693
TP_0551
Phosphatase; Similar to GB:L25421 PID:409159 percent identity: 32.50; identified by sequence similarity; putative.
  
    0.539
mnmE
Thiophene and furan oxidation protein (thdF); Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
       0.509
flgG1
Flagellar basal-body rod protein (flgG-1); Similar to GB:AE000783 percent identity: 62.12; identified by sequence similarity; putative.
    
   0.472
flgG2
Flagellar basal-body rod protein (flgG-2); Similar to GB:AE000783 percent identity: 50.37; identified by sequence similarity; putative.
    
   0.472
TP_0552
Predicted coding region TP0552; Hypothetical protein; identified by Glimmer; putative.
       0.459
TP_0622
Predicted coding region TP0622; Hypothetical protein; identified by Glimmer; putative.
 
     0.415
TP_0600
Zinc protease, putative; Similar to GB:L42023 SP:P44936 PID:1006037 PID:1221023 PID:1205165 percent identity: 32.94; identified by sequence similarity; putative; Belongs to the peptidase M50B family.
 
     0.404
TP_0920
Predicted coding region TP0920; Hypothetical protein; identified by Glimmer; putative.
 
     0.400
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.