STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gphPhosphoglycolate phosphatase (gph-2); Similar to GB:L42023 SP:P44755 PID:1004013 PID:1222502 PID:1204815 percent identity: 32.55; identified by sequence similarity; putative. (222 aa)    
Predicted Functional Partners:
TP_0407
Phosphoglycolate phosphatase (gph-1); Similar to SP:P32662 GB:Z19601 PID:41223 PID:606319 GB:U00096 percent identity: 31.64; identified by sequence similarity; putative.
    
 0.924
flgD
Flagellar hook assembly scaffolding protein (flgD); Similar to GP:2196902 percent identity: 100.00; identified by sequence similarity; putative.
    
   0.761
rpe
Ribulose-phosphate 3-epimerase (cfxE); Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate; Belongs to the ribulose-phosphate 3-epimerase family.
  
  
 0.729
TP_0290
Conserved hypothetical protein; Similar to GP:1418999 percent identity: 27.07; identified by sequence similarity; putative.
    
  0.725
ldhD
D-specific D-2-hydroxyacid dehydrogenase; Similar to GP:1644433 percent identity: 42.48; identified by sequence similarity; putative.
    
  0.723
TP_0939
Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative.
     
 0.709
mtnN
Pfs protein (pfs); Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
  
 
  0.700
TP_0553
Conserved hypothetical integral membrane protein; Similar to GB:AE000511 PID:2313674 percent identity: 27.87; identified by sequence similarity; putative.
       0.693
atpE
V-type ATPase, subunit E, putative; Produces ATP from ADP in the presence of a proton gradient across the membrane.
     
  0.690
TP_0531
V-type ATPase, subunit F, putative; Similar to PID:1199637 SP:Q60185 percent identity: 31.63; identified by sequence similarity; putative.
     
  0.690
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.