STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gphPhosphoglycolate phosphatase (gph-2); Similar to GB:L42023 SP:P44755 PID:1004013 PID:1222502 PID:1204815 percent identity: 32.55; identified by sequence similarity; putative. (222 aa)    
Predicted Functional Partners:
TP_0407
Phosphoglycolate phosphatase (gph-1); Similar to SP:P32662 GB:Z19601 PID:41223 PID:606319 GB:U00096 percent identity: 31.64; identified by sequence similarity; putative.
    
 0.938
TP_0939
Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative.
     
 0.805
flgD
Flagellar hook assembly scaffolding protein (flgD); Similar to GP:2196902 percent identity: 100.00; identified by sequence similarity; putative.
    
   0.769
rpe
Ribulose-phosphate 3-epimerase (cfxE); Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate; Belongs to the ribulose-phosphate 3-epimerase family.
  
  
 0.698
TP_0553
Conserved hypothetical integral membrane protein; Similar to GB:AE000511 PID:2313674 percent identity: 27.87; identified by sequence similarity; putative.
       0.693
cmk
Ribosomal protein S1 (rpsA); Similar to SP:P02349 GB:V00342 GB:V00352 GB:X04864 PID:42837 percent identity: 36.77; identified by sequence similarity; putative.
  
 
  0.687
TP_0085
PTS system, nitrogen regulatory IIA component (ptsN-1); Similar to GB:X16474 SP:P33670 PID:405792 percent identity: 26.35; identified by sequence similarity; putative.
   
  0.655
ispDF
Conserved hypothetical protein; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF); In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
  
   0.616
TP_0290
Conserved hypothetical protein; Similar to GP:1418999 percent identity: 27.07; identified by sequence similarity; putative.
    
  0.615
ldhD
D-specific D-2-hydroxyacid dehydrogenase; Similar to GP:1644433 percent identity: 42.48; identified by sequence similarity; putative.
    
  0.612
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.