STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
asnAAsparagine synthetase (asnA); Similar to GB:L42023 SP:P44338 PID:1004011 PID:1222501 PID:1204814 percent identity: 72.12; identified by sequence similarity; putative. (330 aa)    
Predicted Functional Partners:
TP_0223
Aspartate aminotransferase (tpaaT); Similar to GP:2104501 percent identity: 99.77; identified by sequence similarity; putative.
     
 0.844
nadE
NH(3)-dependent NAD(+) synthetase (nadE); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.
    
  0.678
TP_0557
Conserved hypothetical protein; Similar to GB:M55917 SP:P22041 PID:152899 percent identity: 30.71; identified by sequence similarity; putative.
       0.543
nicO
Conserved hypothetical integral membrane protein; Similar to GB:L42023 SP:P44136 PID:1007168 PID:1221377 PID:1205489 percent identity: 24.48; identified by sequence similarity; putative; Belongs to the NiCoT transporter (TC 2.A.52) family.
       0.480
TP_0555
Glutamate/ aspartate transporter, putative; Similar to SP:P51906 percent identity: 28.69; identified by sequence similarity; putative; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
       0.437
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.