STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0557Conserved hypothetical protein; Similar to GB:M55917 SP:P22041 PID:152899 percent identity: 30.71; identified by sequence similarity; putative. (237 aa)    
Predicted Functional Partners:
nicO
Conserved hypothetical integral membrane protein; Similar to GB:L42023 SP:P44136 PID:1007168 PID:1221377 PID:1205489 percent identity: 24.48; identified by sequence similarity; putative; Belongs to the NiCoT transporter (TC 2.A.52) family.
 
     0.938
TP_1002
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 31.50; identified by sequence similarity; putative.
  
     0.705
TP_0990
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 23.34; identified by sequence similarity; putative.
 
   
 0.607
TP_0408
Predicted coding region TP0408; Hypothetical protein; identified by Glimmer; putative.
  
     0.574
TP_0565
Predicted coding region TP0565; Hypothetical protein; identified by Glimmer; putative.
  
     0.558
asnA
Asparagine synthetase (asnA); Similar to GB:L42023 SP:P44338 PID:1004011 PID:1222501 PID:1204814 percent identity: 72.12; identified by sequence similarity; putative.
       0.543
TP_0392
Conserved hypothetical protein; Similar to PID:1165282 PID:1196311 PID:1234877 GB:AE000783 percent identity: 24.15; identified by sequence similarity; putative.
  
     0.518
thiI
Conserved hypothetical protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
       0.518
TP_0361
Lysophosphatidic acid acyltransferase, putative; Similar to GP:2286207 percent identity: 35.20; identified by sequence similarity; putative.
     
 0.510
TP_0496
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 29.52; identified by sequence similarity; putative.
  
     0.503
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.