STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nicOConserved hypothetical integral membrane protein; Similar to GB:L42023 SP:P44136 PID:1007168 PID:1221377 PID:1205489 percent identity: 24.48; identified by sequence similarity; putative; Belongs to the NiCoT transporter (TC 2.A.52) family. (302 aa)    
Predicted Functional Partners:
TP_0557
Conserved hypothetical protein; Similar to GB:M55917 SP:P22041 PID:152899 percent identity: 30.71; identified by sequence similarity; putative.
 
     0.938
TP_0304
Predicted coding region TP0304; Hypothetical protein; identified by Glimmer; putative.
  
   
 0.710
TP_0930
Predicted coding region TP0930; Hypothetical protein; identified by Glimmer; putative.
  
     0.633
TP_0408
Predicted coding region TP0408; Hypothetical protein; identified by Glimmer; putative.
  
     0.631
tmpB
Outer membrane protein (tmpB); Tmp may serve as a porin or transport protein for large molecules; To T.phagedenis TmpB.
  
     0.595
thiI
Conserved hypothetical protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
       0.588
TP_0095
Predicted coding region TP0095; Hypothetical protein; identified by Glimmer; putative.
 
     0.580
TP_0346
Predicted coding region TP0346; Hypothetical protein; identified by Glimmer; putative.
      
 0.580
TP_0481
Predicted coding region TP0481; Hypothetical protein; identified by Glimmer; putative.
  
     0.573
TP_0990
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 23.34; identified by sequence similarity; putative.
  
     0.564
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.