Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TP_0561Conserved hypothetical protein; Similar to PID:882672 SP:P55140 GB:U00096 PID:1789140 percent identity: 36.96; identified by sequence similarity; putative. (283 aa)    
Predicted Functional Partners:
fliL
Flagellar protein (fliL); Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
    
 
 0.831
TP_0570
Predicted coding region TP0570; Hypothetical protein; identified by Glimmer; putative.
 
     0.822
TP_0571
Tp70 protein; Similar to GB:X61227 PID:48231 percent identity: 96.67; identified by sequence similarity; putative.
 
    0.822
flhB
Flagellar biosynthetic protein (flhB); Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin (By similarity); Belongs to the type III secretion exporter family.
    
 
 0.799
fliR
Flagellar biosynthetic protein (fliR); Role in flagellar biosynthesis; Belongs to the FliR/MopE/SpaR family.
    
 
 0.798
fliQ
Flagellar biosynthetic protein (fliQ); Role in flagellar biosynthesis; Belongs to the FliQ/MopD/SpaQ family.
    
 
 0.798
fliF
Flagellar basal-body M ring protein (fliF); The M ring may be actively involved in energy transduction.
    
   0.761
TP_0564
Predicted coding region TP0564; Hypothetical protein; identified by Glimmer; putative.
   
   0.681
tkt
Transketolase A (tktA); Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
    0.533
spsE
Spore coat polysaccharide biosynthesis protein (spsE); Similar to GB:X73124 SP:P39625 PID:413991 GB:AL009126 percent identity: 27.64; identified by sequence similarity; putative.
       0.512
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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