STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TP_0567Conserved hypothetical protein; Similar to PID:1165270 PID:1196323 GB:AE000783 percent identity: 30.48; identified by sequence similarity; putative. (206 aa)    
Predicted Functional Partners:
fliF
Flagellar basal-body M ring protein (fliF); The M ring may be actively involved in energy transduction.
 
    0.983
fliY
Flagellar motor switch protein (fliY); FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.
  
    0.973
flgK
Flagellar hook-associated protein 1 (flgK); Similar to SP:P70859 PID:1518046 GB:AE000783 percent identity: 39.78; identified by sequence similarity; putative.
 
    0.971
flgE
Flagellar hook protein (flgE); Similar to GP:2196893 percent identity: 100.00; identified by sequence similarity; putative.
 
  
 0.968
fliK
Treponemal aqueous protein (tap1); Similar to GP:2196901 percent identity: 100.00; identified by sequence similarity; putative.
  
  
 0.966
fliH
Flagellar assembly protein (fliH); Needed for flagellar regrowth and assembly; Belongs to the FliH family.
 
    0.963
fliO
Hypothetical protein; Similar to PID:1216382 PID:973196 percent identity: 100.00; identified by sequence similarity; putative.
 
  
 0.958
flgB
Flagellar basal-body rod protein (flgB); Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
 
  
 0.956
fliL
Flagellar protein (fliL); Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
  
 
 0.952
motA
Flagellar motor rotation protein (motA); MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel (By similarity).
  
  
 0.946
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.