STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0571Tp70 protein; Similar to GB:X61227 PID:48231 percent identity: 96.67; identified by sequence similarity; putative. (221 aa)    
Predicted Functional Partners:
TP_0570
Predicted coding region TP0570; Hypothetical protein; identified by Glimmer; putative.
 
     0.835
TP_0561
Conserved hypothetical protein; Similar to PID:882672 SP:P55140 GB:U00096 PID:1789140 percent identity: 36.96; identified by sequence similarity; putative.
 
    0.788
TP_0572
Predicted coding region TP0572; Hypothetical protein; identified by Glimmer; putative.
       0.733
pepP
Similar to GP:2584787 percent identity: 37.52; identified by sequence similarity; putative.
  
    0.638
TP_0574
Carboxypeptidase, 47 kDa; A possible D,D-carboxypeptidase, that releases amino acids sequentially from a proteins C-terminus. Has zinc-dependent carboxypeptidase activity on synthetic depsipeptide substrates. May serve to decrease cross-linking of peptidoglycan, promoting the highly sinusous motility of this spirochaete (Probable). Overexpression of the whole protein in E.coli leads to aberrant cell morphology and extrusion of the cytoplasm, while overexpression of a construct with the first 62 resides of the protein fused to PhoA does have this effect, suggesting the whole protein, no [...]
       0.491
eda
4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxyphosphogluconate aldolase (eda); Similar to GB:L42023 PID:1004194 PID:1221953 PID:1204305 SP:P44480 percent identity: 43.63; identified by sequence similarity; putative; Belongs to the KHG/KDPG aldolase family.
       0.420
TP_0711
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 27.11; identified by sequence similarity; putative.
   
   0.401
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.