STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TP_0572Predicted coding region TP0572; Hypothetical protein; identified by Glimmer; putative. (360 aa)    
Predicted Functional Partners:
apbE
Conserved hypothetical protein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein (By similarity). Displays FAD pyrophosphatase activity in vitro, hydrolyzing FAD into FMN and AMP.
 
  
 0.792
TP_0571
Tp70 protein; Similar to GB:X61227 PID:48231 percent identity: 96.67; identified by sequence similarity; putative.
       0.733
rnfD
Conserved hypothetical integral membrane protein; Similar to GP:1787917 percent identity: 29.71; identified by sequence similarity; putative.
     
 0.698
ackA
Acetate kinase (ack); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
     
  0.690
TP_0570
Predicted coding region TP0570; Hypothetical protein; identified by Glimmer; putative.
       0.657
pepP
Similar to GP:2584787 percent identity: 37.52; identified by sequence similarity; putative.
 
     0.649
TP_0107
licC protein (licC); Similar to GB:L42023 PID:1007733 PID:1221685 PID:1205774 PID:1574381 percent identity: 29.03; identified by sequence similarity; putative.
  
     0.640
msrAB
protein-methionine-S-oxide reductase (msrA); Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
  
  
 0.595
fldA
Flavodoxin; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.
 
     0.595
TP_0574
Carboxypeptidase, 47 kDa; A possible D,D-carboxypeptidase, that releases amino acids sequentially from a proteins C-terminus. Has zinc-dependent carboxypeptidase activity on synthetic depsipeptide substrates. May serve to decrease cross-linking of peptidoglycan, promoting the highly sinusous motility of this spirochaete (Probable). Overexpression of the whole protein in E.coli leads to aberrant cell morphology and extrusion of the cytoplasm, while overexpression of a construct with the first 62 resides of the protein fused to PhoA does have this effect, suggesting the whole protein, no [...]
       0.589
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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