STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0579Predicted coding region TP0579; Hypothetical protein; identified by Glimmer; putative. (258 aa)    
Predicted Functional Partners:
prfB
Peptide chain release factor 2 (prfB); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
       0.789
TP_0577
Predicted coding region TP0577; Hypothetical protein; identified by Glimmer; putative.
       0.789
ftsY
Cell division protein (ftsY); Similar to SP:P51835 percent identity: 38.16; identified by sequence similarity; putative.
       0.789
lolE1
Conserved hypothetical integral membrane protein; Similar to GB:AE000783 percent identity: 30.77; identified by sequence similarity; putative.
       0.786
lolD
ABC transporter, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
       0.786
lolE2
Conserved hypothetical integral membrane protein; Similar to GB:AE000783 percent identity: 23.27; identified by sequence similarity; putative.
       0.786
fliE
Flagellar hook-basal body complex protein (fliE); Similar to GP:2105147 percent identity: 58.12; identified by sequence similarity; putative.
    
   0.769
fliY
Flagellar motor switch protein (fliY); FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.
    
   0.769
flgD
Flagellar hook assembly scaffolding protein (flgD); Similar to GP:2196902 percent identity: 100.00; identified by sequence similarity; putative.
    
   0.769
TP_0584
Predicted coding region TP0584; Hypothetical protein; identified by Glimmer; putative.
       0.531
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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