STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lolE2Conserved hypothetical integral membrane protein; Similar to GB:AE000783 percent identity: 23.27; identified by sequence similarity; putative. (495 aa)    
Predicted Functional Partners:
lolD
ABC transporter, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
 
 0.999
lolE1
Conserved hypothetical integral membrane protein; Similar to GB:AE000783 percent identity: 30.77; identified by sequence similarity; putative.
 
  
 
0.990
TP_0964
ABC transporter, ATP-binding protein; Similar to GB:AL009126 percent identity: 49.32; identified by sequence similarity; putative.
 
 0.988
TP_0333
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 31.40; identified by sequence similarity; putative.
 
 
 
 0.955
TP_0789
Predicted coding region TP0789; Hypothetical protein; identified by Glimmer; putative.
 
 
 
 0.943
prfB
Peptide chain release factor 2 (prfB); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
       0.837
ftsY
Cell division protein (ftsY); Similar to SP:P51835 percent identity: 38.16; identified by sequence similarity; putative.
       0.837
TP_0577
Predicted coding region TP0577; Hypothetical protein; identified by Glimmer; putative.
       0.835
tp92
Outer membrane protein; Might be part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane; Belongs to the BamA family.
 
   
 0.805
TP_0579
Predicted coding region TP0579; Hypothetical protein; identified by Glimmer; putative.
       0.786
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.