STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0599Predicted coding region TP0599; Hypothetical protein; identified by Glimmer; putative. (218 aa)    
Predicted Functional Partners:
TP_0600
Zinc protease, putative; Similar to GB:L42023 SP:P44936 PID:1006037 PID:1221023 PID:1205165 percent identity: 32.94; identified by sequence similarity; putative; Belongs to the peptidase M50B family.
       0.832
dxr
Conserved hypothetical protein; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.
       0.832
uppS
Conserved hypothetical protein; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
       0.832
frr
Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.
       0.832
cdsA
Phosphatidate cytidylyltransferase (cdsA); Similar to GB:AE000783 percent identity: 32.47; identified by sequence similarity; putative.
       0.773
TP_0597
Predicted coding region TP0597; Hypothetical protein; identified by Glimmer; putative.
       0.726
TP_0598
Predicted coding region TP0598; Hypothetical protein; identified by Glimmer; putative.
       0.726
tsf
Translation elongation factor TS (tsf); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity); Belongs to the EF-Ts family.
       0.573
pcnB2
Polynucleotide adenylyltransferase (pcnB); Similar to SP:P13685 GB:D26562 GB:M20574 GB:S48039 PID:147117 percent identity: 41.91; identified by sequence similarity; putative; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
       0.449
rpsB
Ribosomal protein S2 (rpsB); Similar to GB:AE000783 percent identity: 58.75; identified by sequence similarity; putative; Belongs to the universal ribosomal protein uS2 family.
       0.424
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.