STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0600Zinc protease, putative; Similar to GB:L42023 SP:P44936 PID:1006037 PID:1221023 PID:1205165 percent identity: 32.94; identified by sequence similarity; putative; Belongs to the peptidase M50B family. (450 aa)    
Predicted Functional Partners:
uppS
Conserved hypothetical protein; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
 
    0.967
cdsA
Phosphatidate cytidylyltransferase (cdsA); Similar to GB:AE000783 percent identity: 32.47; identified by sequence similarity; putative.
  
    0.953
tp92
Outer membrane protein; Might be part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane; Belongs to the BamA family.
 
  
 0.942
dxr
Conserved hypothetical protein; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.
  
  
 0.924
frr
Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.
 
  
 0.908
TP_0599
Predicted coding region TP0599; Hypothetical protein; identified by Glimmer; putative.
       0.832
TP_0487
Predicted coding region TP0487; Hypothetical protein; identified by Glimmer; putative.
  
    0.796
ompH
Cationic outer membrane protein (ompH); Similar to GB:M34854 SP:P31519 PID:155479 percent identity: 22.44; identified by sequence similarity; putative.
  
  
 0.765
TP_0597
Predicted coding region TP0597; Hypothetical protein; identified by Glimmer; putative.
       0.745
TP_0598
Predicted coding region TP0598; Hypothetical protein; identified by Glimmer; putative.
       0.745
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.