STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cdsAPhosphatidate cytidylyltransferase (cdsA); Similar to GB:AE000783 percent identity: 32.47; identified by sequence similarity; putative. (287 aa)    
Predicted Functional Partners:
uppS
Conserved hypothetical protein; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
 
  
 0.977
TP_0361
Lysophosphatidic acid acyltransferase, putative; Similar to GP:2286207 percent identity: 35.20; identified by sequence similarity; putative.
    
 0.964
dxr
Conserved hypothetical protein; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.
  
  
 0.963
TP_0600
Zinc protease, putative; Similar to GB:L42023 SP:P44936 PID:1006037 PID:1221023 PID:1205165 percent identity: 32.94; identified by sequence similarity; putative; Belongs to the peptidase M50B family.
  
  
 0.950
pgsA
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (pgsA); This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
    
 0.941
pgsA2
Conserved hypothetical protein; Similar to PID:2088865 percent identity: 28.12; identified by sequence similarity; putative; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
    
 0.886
TP_0487
Predicted coding region TP0487; Hypothetical protein; identified by Glimmer; putative.
  
  
 0.880
frr
Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.
     
 0.846
TP_0599
Predicted coding region TP0599; Hypothetical protein; identified by Glimmer; putative.
       0.773
ispDF
Conserved hypothetical protein; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF); In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
  
  
 0.734
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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