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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0615Nitrogen fixation protein (nifU); Similar to GB:U00013 PID:466875 PID:2398702 percent identity: 32.43; identified by sequence similarity; putative. (147 aa)    
Predicted Functional Partners:
csd
Nitrogen fixation protein (nifS-1); Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
 
 0.999
nifS
Nitrogen fixation protein (nifS-2); Similar to GB:M86823 SP:Q01179 GB:U22347 PID:151968 percent identity: 38.19; identified by sequence similarity; putative.
  
 0.999
dnaK
Heat shock protein 70 (dnaK); Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.985
sufC
ABC transporter, ATP-binding protein; Similar to PID:1001734 PID:1001706 percent identity: 49.38; identified by sequence similarity; putative.
  
  
 0.965
sufD
Conserved hypothetical protein; Similar to GB:U00013 PID:466874 PID:2398705 percent identity: 25.33; identified by sequence similarity; putative.
  
  
 0.957
sufB
Conserved hypothetical protein; Similar to GB:AL009126 percent identity: 52.16; identified by sequence similarity; putative.
  
  
 0.953
TP_0939
Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative.
  
  
 0.904
rpiA
Ribose 5-phosphate isomerase (rpiA); Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
     
 0.724
trxB
Thioredoxin reductase (trxB); Similar to GB:AL009126 percent identity: 46.10; identified by sequence similarity; putative.
  
 
 0.675
cmk
Ribosomal protein S1 (rpsA); Similar to SP:P02349 GB:V00342 GB:V00352 GB:X04864 PID:42837 percent identity: 36.77; identified by sequence similarity; putative.
     
 0.623
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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