STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cheRChemotaxis protein methyltransferase (cheR); Similar to GB:AE000783 percent identity: 47.10; identified by sequence similarity; putative. (303 aa)    
Predicted Functional Partners:
cheB
Protein-glutamate methylesterase (cheB); Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 0.999
cheA
Chemotaxis histidine kinase (cheA); Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY (By similarity).
 
 
 0.992
mcp2
Methyl-accepting chemotaxis protein (mcp2-1); Similar to GP:2367665 percent identity: 99.77; identified by sequence similarity; putative.
 
 0.987
cheW
Purine-binding chemotaxis protein (cheW-2); Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors.
 
 
 0.980
mcp4
Methyl-accepting chemotaxis protein (mcp2-3); Similar to GP:2352917 percent identity: 29.09; identified by sequence similarity; putative.
 
 0.977
TP_0939
Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative.
   
   0.952
fliY
Flagellar motor switch protein (fliY); FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.
  
 
 0.938
rpoE
RNA polymerase sigma-24 factor (rpoE); Similar to PID:699142 percent identity: 27.89; identified by sequence similarity; putative.
    
 
 0.901
cheW1
Purine-binding chemotaxis protein (cheW-1); Similar to GP:1765974 percent identity: 99.78; identified by sequence similarity; putative.
 
 
0.893
mcp1
Methyl-accepting chemotaxis protein (mcp1); Similar to GP:1354776 percent identity: 100.00; identified by sequence similarity; putative.
 
 0.892
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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