STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lysSlysyl-tRNA synthetase (lysS-1); Similar to GB:AE000783 percent identity: 51.24; identified by sequence similarity; putative; Belongs to the class-I aminoacyl-tRNA synthetase family. (528 aa)    
Predicted Functional Partners:
TP_0645
Predicted coding region TP0645; Hypothetical protein; identified by Glimmer; putative.
       0.678
serS
seryl-tRNA synthetase (serS); Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
  
    0.645
nusG
Transcription antitermination protein (nusG); Participates in transcription elongation, termination and antitermination.
   
    0.625
pyrH
Uridylate kinase (smbA); Catalyzes the reversible phosphorylation of UMP to UDP.
 
     0.620
metG
methionyl-tRNA synthetase (metG); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
     
 0.568
TP_0646
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 24.77; identified by sequence similarity; putative.
       0.529
cmk-2
Cytidylate kinase (cmk); Similar to GB:AE000783 percent identity: 42.53; identified by sequence similarity; putative.
  
     0.513
TP_0931
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 50.42; identified by sequence similarity; putative.
  
     0.487
leuS
leucyl-tRNA synthetase (leuS); Similar to GB:AE000783 percent identity: 50.60; identified by sequence similarity; putative; Belongs to the class-I aminoacyl-tRNA synthetase family.
   
   0.451
rplS
Ribosomal protein L19 (rplS); This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
   
    0.448
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.