STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
potBSpermidine/putrescine ABC transporter, permease protein (potB); Similar to GB:AE000782 percent identity: 29.22; identified by sequence similarity; putative. (299 aa)    
Predicted Functional Partners:
potA
Spermidine/putrescine ABC transporter, ATP-binding protein (potA); Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
 0.999
potC
Spermidine/putrescine ABC transporter, permease protein (potC); Similar to GB:L42023 SP:P45169 PID:1007355 PID:1221477 PID:1205581 percent identity: 40.16; identified by sequence similarity; putative.
 
0.999
potD
Spermidine/putrescine ABC transporter, periplasmic binding protein (potD); Similar to GB:M64519 SP:P23861 PID:147329 GB:U00096 PID:1651550 percent identity: 31.38; identified by sequence similarity; putative.
 
 
 0.999
TP_0142
Thiamine ABC transporter, ATP-binding protein, putative; Similar to GB:L42023 SP:P45171 PID:1007359 PID:1221479 PID:1205583 percent identity: 36.19; identified by sequence similarity; putative.
 0.956
TP_0804
Sugar ABC transporter, ATP-binding protein (ugpC); Similar to SP:P10907 GB:U00039 PID:43249 PID:912455 GB:U00096 percent identity: 47.77; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily.
   
 0.743
sbcC
Exonuclease (sbcC); SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity (By similarity); Belongs to the SMC family. SbcC subfamily.
    
  0.666
TP_0076
Sugar ABC transporter, permease protein (y4oR); Similar to SP:P55603 PID:2182562 percent identity: 35.38; identified by sequence similarity; putative.
   
 
  0.621
ybeY
Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
       0.561
metK
S-adenosylmethionine synthetase (metK); Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
     
 0.543
serS
seryl-tRNA synthetase (serS); Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
  
    0.529
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.